Frank Detomello is a slovenly zoo keeper, and simple father to the only young and bright girl named Shane, who catches a cold right after he swallowed a germ-ridden egg! The inside of his body is known as the "City of Frank". An unlikely hero of a policeman white blood cell, by the name of Osmosis Jones, works as a member of Immunity cell. But with that germ-ridden egg comes a mortal danger: Osmosis discovers Frank has really contracted a villainous and black-hearted deadly virus known as Thrax who arrives and is plotting to ultimately overheat Frank's body, killing him from the inside out! Thrax is motivated by trying to become the nastiest new virus, attempting to kill each new victim faster than the previous. His grandiose plan for Frank is death in 48 hours, breaking previous medical records! Meanwhile the pill that Frank took, Drix arrives in the body and covers Frank's throat with ice to cover the irritation. Osmosis Jones becomes his newest partner. Now it's all up to only ...Written by
Anthony Pereyra <email@example.com>
The last 2D animated feature film released by Warner Bros. pictures, and the final film of Warner Bros. feature animation up until Teen Titans Go to the Movies (2018). See more »
When Osmosis comes back from "The Zit" he greets Leah by saying "Brandy- oh I mean Leah". Brandy Norwood was the voice of Leah. The error was left in because it was acted so well and was funny. See more »
Son, do me a favor and read what it says on your arm.
'For the temporary relief of symptoms associated with... '
Exactly! Temporary. You're nothing but a wannabe, a placebo, a generic brand. Marked-down, over-the-counter, useless Tic-Tac!
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The title appears as bubbles, which then pop after 5 seconds. See more »
The DVD release contains three extended (and half-animated) scenes, all of which appear in cut-down form in the final edit:
Drix and Jones visit the eyes, while Drix complains that he has to visit the nose and the throat. Jones gets donuts and calls the infodesk on his cell phone while at the eyes.
Frank picks his nose during the dam-bursting sequence, and Jones saves Drix from ending up on Frank's fingertip. In the end, they're snorted back up into the sinuses.
The race to catch Thrax on his way to the uvula is extended; we see Thrax leap from his car and glide away. Then, after Jones takes the wrong turn, he takes a "shortcut" to the uvula by way of the esophogus, riding a massive acidic Frank-belch up the throat.
A Great Class of Hygienic and Human Body Functions
Frank (Bill Murray) is a widow without hygienic and bad alimentary habits. He eats food that felt on the floor without cleaning, he does not wash his hands before eating and he eats only junk food. His daughter keeps unsuccessfully trying to correct his behavior. One day, Frank eats a dirty egg and gets a disease. From this moment on, the human body functions are showed through very funny and educational cartoons. The hero, Osmosis Jones, is a white globule, with Chris Rock's voice. The great Farrely brothers again surprise me. This funny (and sometimes scatological movie) is a great class of hygienic and human body functions. Chris Rock and Laurence Fishburne give a great performance with their voices. Bill Murry has the role of a disgusting character. An excellent and very educational movie, indicated also (or specially) for children. My vote is nine.
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